The 5-Second Trick For pentobarbital sodium drug class
The 5-Second Trick For pentobarbital sodium drug class
Blog Article
pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of CYP3A4 inducers might minimize sufentanil concentrations and efficacy, maybe precipitating withdrawal syndrome in clients who have formulated physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers may possibly boost sufentanil plasma concentration.
pentobarbital will reduce the level or effect of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or effect of docetaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will decrease the extent or effect of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to your lower in fentanyl plasma concentrations, not enough efficacy or, perhaps, development of a withdrawal syndrome in the affected individual who has developed Actual physical dependence to fentanyl.
DOSAGE AND ADMINISTRATION Dosages of barbiturates have to be individualized with full knowledge of their distinct qualities and recommended price of administration.
pentobarbital will lessen the level or effect of armodafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will decrease the level or effect of tamoxifen by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
Nursing mothers: Caution really should be exercised every time a barbiturate is administered to your nursing lady given that modest quantities of barbiturates are excreted while in the milk.
pentobarbital will minimize the extent or effect of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or effect of theophylline by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Sodium valproate and valproic acid show up to decrease barbiturate metabolism; thus, barbiturate blood levels must be monitored and appropriate dosage adjustments manufactured as indicated.
pentobarbital will lower the extent or effect of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.
pentobarbital will lower the extent or effect of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir may be lessened if coadministered with solid CYP3A inducers and is also consequently contraindicated.
fentanyl transdermal and pentobarbital both improve sedation. Stay away from or Use check here Alternate Drug. Limit use to sufferers for whom alternative treatment method possibilities are inadequate